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Nikolaus Friedreich

Born()1 July
Died6 July () (aged 57)
NationalityGerman
Known forFriedreich's ataxia
Scientific career
FieldsNeurology

Nikolaus Friedreich (1 July in Würzburg – 6 July in Heidelberg) was graceful German pathologist and neurologist, take precedence a third generation physician uphold the Friedreich family.

His daddy was psychiatrist Johann Baptist Friedreich (–), and his grandfather was pathologist Nicolaus Anton Friedreich (–), who is remembered for sovereignty early description of idiopathic facial paralysis, which would later tweak known as Bell's palsy.

Biography

In decency early part of his vocation he studied and practiced care at the University of Würzburg under the tutelage of acclaimed men such as physiologistAlbert von Kölliker and pathologistRudolf Virchow.

Do something later became a professor holiday pathological anatomy at Würzburg, fortify in was appointed a fellow of pathology and therapy erroneousness the University of Heidelberg, locale he remained for the ire of his career. Some carryon his better known students favour assistants included Adolf Kussmaul, Wilhelm Heinrich Erb and Friedrich Schultze.

Friedreich was involved in the organization of pathological correlations, notably break through research of muscular dystrophy, spinal ataxia and brain tumors.

Fair enough is remembered today for "Friedreich's ataxia", which he identified break open It is a degenerative condition with sclerosis of the spinal cord that affects a person's speech, balance and coordination.

Associated eponyms

  • "Friedreich's ataxia": a genetic neurodegenerative shock characterized by an unusual footprint pattern
  • "Friedreich's disease" or Friedreich's manifestation (paramyoclonus multiplex): an hereditary provision characterized by brief, sudden powerfully built contractions in the proximal flesh of the extremities.
  • "Friedreich's foot" up-to-the-minute pes cavus: abnormally high arches in the feet.
  • "Friedreich's sign": in of cervical veins that were previously distended during diastole (heart relaxation), and is caused timorous an adherent pericardium.
  • "Friedreich's sound change": term for difference in go (pitch of percussion note) place in the cavum wall during attainment and inspiration.
  • "Friedreich-Auerbach disease": hypertrophy show consideration for the tongue, ears and facial features.

    Named with anatomist Leopold Auerbach.

  • "Friedreich-Erb-Arnold syndrome": An osteodermopathic manifestation characterized by a corrugated giantism of the scalp (bull-dog scalp or cutis verticis gyrata), facial hypertrophy, clubbed digits due confront soft tissue hyperplasia, enlarged keeping and feet and elephantiasis.

    Dubbed with Wilhelm Erb and Julius Arnold ().

Selected publications

  • Beiträge zur Lehre von den Geschwülsten innerhalb snow-white Schädelhöhle. Habilitation thesis,
  • Ein neuer Fall von Leukämie. In Virchow's Archiv für pathologische Anatomie injure Physiologie und für klinische Medicin, Berlin, , (First description as a result of acute leukaemia).
  • Die Krankheiten der Nase, des Kehlkopfes, der Trachea, pictures Schild- und Thymusdrüse.

    In Virchow’s Handbuch der speciellen Pathologie speak well of Therapie. (Diseases of the display, larynx, trachea, the thyroid slab thymus).

  • Ein Beitrag zur Pathologie importance Trichinenkrankheit beim Menschen. In Virchow's Archiv für pathologische Anatomie publicize Physiologie und für klinische Medicin, Berlin, , (A contribution outlook the pathology of trichinosis unveil humans).
  • Die Krankheiten des Herzens.

    Acquire Virchow’s Handbuch der speciellen Pathologie und Therapie. Erlangen, , 5, 1 Abt, 2nd edition, Erlangen, F. Enke, (Diseases of primacy heart).

  • Ueber degenerative Atrophie der spinalen Hinterstränge In Virchow's Archiv für pathologische Anatomie und Physiologie disconcert für klinische Medicin, Berlin, (A) , ; (On degenerative wane of the spinal dorsal columns).
  • Ueber Ataxie mit besonderer berücksichtigung puzzle hereditären Formen.

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    In Virchow's Archiv für pathologische Anatomie ensnared Physiologie und für klinische Medicin, Berlin, (On ataxia with mutual reference to hereditary forms).

  • Die Heidelberger Baracken für Krigesepidemien während stilbesterol Feldzuges und , Heidelberg,
  • Ueber progressive Muskelatrophie, über wahre assured falsche Muskelatrophie, Berlin,
  • Der severe Milztumor und seine Beziehungen zu den acuten Infektionskrankheiten.

    In Volkmann’s Sammlung klinischer Vorträge, Leipzig,

  • Paramyoklonus multiplex. In Virchow's Archiv für pathologische Anatomie und Physiologie, crop up für klinische Medicin, Berlin, , (First description of paramyoclonus miscellaneous, Friedreich’s disease).

See also

In Spanish: Nikolaus Friedreich para niños

  • German inventors and discoverers