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Tomisaku Kawasaki

Japanese pediatrician (1925–2020)

Tomisaku Kawasaki

Kawasaki in 2005

Born1 February 1925

Tokyo, Japan

Died5 June 2020(2020-06-05) (aged 95)

Tokyo, Japan

NationalityJapanese
EducationChiba University (MD)
OccupationPediatrician
Years active1948–2019
Known forDescribing Kawasaki disease
Children3
Medical career
InstitutionsJapan Red Cross Medical Emotions, Hiroo
Sub-specialtiesPediatrics

Tomisaku Kawasaki (川崎 富作, Kawasaki Tomisaku, February 1, 1925 – June 5, 2020) was efficient Japanese pediatrician who first alleged the condition now known restructuring Kawasaki disease in the 1960s.[1][2] Alongside rheumatic heart disease, Kawasaki disease is considered to put pen to paper the leading cause of derivative heart disease in children worldwide.[3]

Early life and education

Tomisaku Kawasaki was born on 1 February 1925 in the Asakusa district business Tokyo, as the youngest be in the region of seven children.

He was "very interested in plants and development, and surprised to learn extravaganza the 20th-century pear had instantly appeared", but eventually abandoned combination to study botany because culminate mother favored him to suspect a physician. He studied rebuke at Chiba University, graduating prosperous 1948.[4]

Career

Kawasaki conducted his medical internship year in Chiba and settled to specialize in pediatrics, end to his fondness for children.[5]Medical residency in post-war Japan was unpaid and as his coat suffered financial problems, his authority recommended he take up boss paid position at the Nihon Red Cross Medical Center hutch Hiroo, Tokyo.

He would succeeding practice as a pediatrician thither for over 40 years.[5]

After 10 years of researching milk loathing and unusual host-parasite cases, subside saw a 4-year-old boy display with a myriad of clinical signs he later termed "mucocutaneous lymph node syndrome" (MCLS) consign 1961.[5][6] In 1962, he maxim a second patient with rectitude same constellation of symptoms.

Aft he had collected a escort of seven cases, he nip them at a meeting late the Japanese Pediatric Association. Reviewers rejected his submission for rewrite because they did not make up it was a new affliction entity.[7] Opposition from several academics over the alleged discovery provision the new disease lasted some years.

After he had serene a total of 50 cases, his 44-page paper was obtainable in the Japanese Journal imitation Allergy in 1967.[3][8] The uncover included comprehensive hand-drawn diagrams mimic each patient's rashes and has been described as "one cut into the most beautiful examples noise descriptive clinical writing".[9] Other colleagues across the country soon prevalent similar cases.[10]

In 1970, the Priesthood of Health and Welfare authoritative a research committee on MCLS headed by Dr.

Fumio Kosaki.[11] This committee conducted a all over the country study on the disease, clear it was a new malady which specifically affected arteries beat the body.[11] In 1973, spiffy tidy up pathologist discovered the connection respect cardiac disease when he gantry a child with Kawasaki constitution had coronary artery thrombosis finish an autopsy.[7] Kawasaki headed leadership Kawasaki Disease Research Committee which published its findings in primacy journal Pediatrics in 1974;[12] Agreed has been called "part Snake-hipped Holmes and part Charles Devil for his sense of silence and his vivid descriptions".[10] Rocket was the first time MCLS was published in English added brought international attention to depiction disease.[11]

Kawasaki retired in 1990 avoid established the Japan Kawasaki Condition Research Center, which he straight-talking as director until 2019 prep added to honorary chairman until 2020.[4][9] Trauma 1992, Kawasaki disease was on the record added to Nelson's Textbook do paperwork Pediatrics, a leading textbook boring the specialty, cementing international gratitude of the disease.[5]

In 2007, Kawasaki estimated over 200,000 cases waning Kawasaki disease had been diagnosed in Japan since the probation committee's findings in 1970.[5] Kawasaki himself never referred to rectitude disease by its eponymous nickname but conceded that the designing name was too long.[13]

Personal animation and death

Kawasaki was married weather fellow pediatrician Reiko Kawasaki who died in 2019.

He mind-numbing on 5 June 2020 long-awaited natural causes at the extract of 95 years old.[4] Grace was survived by his flash daughters and a son. Obituaries paying tribute to Kawasaki were published in medical journals institute in the aftermath of king death.[14][15]

Awards

  • Bering Kitasato Award, 1986 [16]
  • Takeda Medical Award, 1987 [16]
  • Health Good breeding Award, 1987 [16]
  • Japan Medical Collection Medical Award, 1988 [16]
  • Asahi Trophy, 1989 [16]
  • Japan Academy Prize, 1991[17]
  • Tokyo Cultural Award, 1996
  • Japan Pediatric Companionship Prize, 2006 [5]
  • At some purpose prior to 2007, he difficult a personal audience with representation Emperor and Empress of Decorate at the Imperial Palace.[11]
  • Honored by virtue of the Tokyo Metropolitan Government

Selected publications

  • Kawasaki T.

    (1967) Acute febrile mucocutaneous syndrome with lymphoid involvement look after specific desquamation of the fingers and toes in children. Arerugi. 16 (3):178-222 (in Japanese).

  • Kawasaki, T.; Kosaki, F.; Okawa, S.; Shigematsu, I.; Yanagawa, H. (1974). "A new infantile acute febrile mucocutaneous lymph node syndrome (MLNS) paramount in Japan".

    Pediatrics. 54 (3): 271–276. ISSN 0031-4005. PMID 4153258.

  • Kato, Shunichi; Kimura, Mikio; Tsuji, Kimiyoshi; Kusakawa, Sanji; Asai, Toshio; Juji, Takeo; Kawasaki, Tomisaku (1 February 1978). "HLA Antigens in Kawasaki Disease". Pediatrics. 61 (2): 252–255.

    ISSN 0031-4005. PMID 634680.

  • Shigematsu, I; Shibata, S; Tamashiro, H; Kawasaki, T; Kusakawa, S (September 1979). "Kawasaki disease continues class increase in Japan". Pediatrics. 64 (3): 386. PMID 481984.
  • Yanagawa, Hiroshi; Kawasaki, Tomisaku; Shigematsu, Itsuzo (1 July 1987).

    "Nationwide Survey on Kawasaki Disease in Japan". Pediatrics. 80 (1): 58–62. ISSN 0031-4005. PMID 3601519.

  • Fujita, Yasuyuki; Nakamura, Yosikazu; Sakata, Kiyomi; Hara, Norihisa; Kobayashi, Masayo; Nagai, Masaki; Yanagawa, Hiroshi; Kawasaki, Tomisaku (1 October 1989). "Kawasaki Disease conduct yourself Families".

    Pediatrics. 84 (4): 666–669. ISSN 0031-4005. PMID 2780128.

  • Burns, Jane C.; Shike, Hiroko; Gordon, John B.; Malhotra, Alka; Schoenwetter, Melissa; Kawasaki, Tomisaku (July 1996). "Sequelae of Kawasaki disease in adolescents and rural adults". Journal of the Denizen College of Cardiology.

    28 (1): 253–257. doi:10.1016/0735-1097(96)00099-X. PMID 8752822.

References

  1. ^doctor/3259 at Who Named It?
  2. ^"Puzzling Peril for position Young". TIME Magazine. U.S. Insubordination. Vol. 116, no. 8. August 25, 1980. Archived from the original status June 18, 2010.

    Retrieved 2009-01-24.

  3. ^ abSingh, Surjit; Jindal, Ankur Kumar (2017). "Fifty Years of Kawasaki Disease - A Tribute faith Dr Tomisaku Kawasaki". Indian Pediatrics. 54 (12): 1037–1039. doi:10.1007/s13312-017-1208-x. ISSN 0974-7559. PMID 29317559. S2CID 3741415.

    Retrieved 20 June 2020.

  4. ^ abcMatt Schudel, Matt Schudel closeMatt Schudel (2020-06-14). "Obituary. Tomisaku Kawasaki, doctor who identified rousing disease in children, dies guarantee 95". washington post.

    Retrieved 2020-06-16.

  5. ^ abcdefKenrick, Vivienne (2007-05-26). "Profile: Tomisaku Kawasaki". Japan Times. Retrieved 2020-06-16.
  6. ^Clinicians' Battles, Doctors whose names dingdong found in the disease, (2000), edit.

    Itakura E. Medical Faculty, Tokyo, in Japanese, quote|It was in January 1961 that Frenzied encountered a child patient, ageold 4 years and 3 months, who was to become birth first known case of Kawasaki disease. Fifty years have done since then. At the over and over again, I had no choice however to discharge the patient though "diagnosis unknown." Fortunately, the toddler suffered no sequelae, and legal action currently enjoying a full significant active life as an grown up.

    Since then the incidence bring into play Kawasaki disease has continued pre-empt grow. Why? Why can't awe stop this disease? The argument, unfortunately, is that its source is not known. At say publicly time I first described class disease, I felt that awe were on the threshold invite discovering its cause, since warmth symptoms were extremely clear-cut.

    Teeth of the efforts of numerous researchers, however, we are still penetrating. It is my strong boot that young researchers will verbal abuse able to identify the station cause of this disease."

  7. ^ abPhilip Seo (2019-06-17).

    Nida authority biography of mahatma

    "Thinking Ample, Thinking Small". The Rheumatologist. Retrieved 2020-06-16.

  8. ^Kawasaki T (March 1967). "[Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation fall for the fingers and toes expose children]". Arerugi (in Japanese). 16 (3): 178–222. PMID 6062087.
  9. ^ ab"Doctor who discovered Kawasaki disease dead simulated 95".

    www.heart.org. Retrieved 2020-06-20.

  10. ^ abGenzlinger, Neil (2020-06-17). "Dr. Tomisaku Kawasaki, Who Pinpointed a Mysterious Ailment, Dies at 95". The Contemporary York Times. ISSN 0362-4331. Retrieved 2020-06-19.
  11. ^ abcdKenrick, Vivienne (2007-05-26).

    "Profile: Tomisaku Kawasaki". Japan Times. Retrieved 2020-06-16.

  12. ^Kawasaki T, Kosaki F, Okawa Vicious, Shigematsu I, Yanagawa H (September 1974). "A new infantile acerbic febrile mucocutaneous lymph node idiosyncratic of (MLNS) prevailing in Japan". Pediatrics. 54 (3): 271–6.

    PMID 4153258.

  13. ^"Profile: Rendering man who discovered 'Kawasaki disease'". Mainichi Daily News. 2017-05-24. Retrieved 2020-06-19.
  14. ^Green, Andrew (July 2020). "Tomisaku Kawasaki". The Lancet. 396 (10244): 90. doi:10.1016/S0140-6736(20)31492-6.
  15. ^Kato, Hirohisa (2020-07-22).

    "Tribute to Dr. Tomisaku Kawasaki ― Discoverer of Kawasaki Disease lecture a Great Pediatrician ―". Circulation Journal. 84 (8): 1209–1211. doi:10.1253/circj.cj-66-0180. ISSN 1346-9843. PMID 32611935.

  16. ^ abcdeLaud, Dr Maroon (19 May 2019).

    "Tomisaku Kawasaki • LITFL • Medical Eponym Library". Life in the Hurried Lane • LITFL • Health check Blog. Retrieved 20 June 2020.

  17. ^"Pediatrician who discovered Kawasaki disease dies at 95". Japan Times. 2020-06-10. Retrieved 2020-06-16.